A new, simple, precise and accurate method for the estimation of Albendazole in bulk and pharmaceutical dosage forms has been developed. 0.1N HCl was chosen as the solvent system. The λmax was found to be 230nm. The responses were linear in the range of 10-70µg/ml. The regression equation of the calibration graph and correlation coefficient were found to be y = 0.032x + 0.014 and 0.999 respectively. The proposed method was statistically validated in order to demonstrate the accuracy, precision, interday and intraday assay, robustness, and ruggedness. The %RSD values for both intraday and interday precision were less than 1%. The recovery of the drug from the sample was ranged between 97.792% and 100.49%. Different commercial formulation (tablets) containing 400mg of Albendazole (BANDY, BENDEX, NOWORM, and ANTHEL) were analyzed by the proposed method and the results were found to be satisfactorily within the claimed limits. This method can be used for the routine estimation of Albendazole in industries and other analytical laboratories and also in dissolution studies.
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